3:50 pm - Wednesday February 18, 5187

New Study Suggests: Pre-School Wheeze likely absent in Babies eating Fish


Children who consumed fish before reaching nine months of age are less prone to suffer Pre-school Wheeze is rare in children devouring fishfrom pre-school wheeze. But they face a higher risk in case they were treated with broad-spectrum antibiotics within the first week of being born or their mother took paracetamol during pregnancy. The researchers analyzed responses from four thousand one hundred & seventy one families that were randomly selected.

The lead author Dr Emma G from the Queen Silvia Children’s Hospital, University of Gothenburg, Sweden, says, “Recurrent wheeze is a very common clinical problem in preschool children and there is a need for better medical treatment and improved understanding of the underlying mechanisms. The aim of our study was to identify both important risk factors and protective factors for the disease.”

The study particularly examined children with three or more episodes of wheezing within the last year. These included children who did and did not use asthma medication such as inhaled corticosteroid. These children were compared with those who did not wheeze.

This wheezy sample was further broken down into children who only developed episodic viral wheeze when they had colds and multiple trigger wheezes. The other group of children also wheezed when they didn’t have a cold, reacting to factors such as exercise, tobacco, allergens or smoke.

“The aim of this study was to determine the risk factors for pre-school wheeze, with particular reference to prenatal paracetamol use, early exposure to antibiotics and fish consumption. A secondary aim was to analyze possible differences between multiple-trigger wheeze and episodic viral wheeze.

“Our findings clearly show that while fish has a protective effect against developing pre-school wheeze, children who had antibiotics in the first week of life and whose mothers took paracetamol during pregnancy faced an increased risk, particularly of multiple-trigger wheeze.”

The study found that one in five children who were part of the study had at least one episode of wheezing and one in twenty had recurrent wheeze that involved three or more episodes over the last year.

Three-quarters of these children had used asthma medication and just over half reported asthma diagnosed by a doctor.

Likelihood of experiencing recurrent wheeze at four & half years age was halved in those eating fish before age of nine months.

Treatment including broad-spectrum antibiotics in the first week was associated with twice the risk of recurrent wheeze at four & half years.

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